ATI Pharmacology, Emergency, & Critical Care Proctored Exam – Spring 2025”Exam Code: NURS-450-003

ATI Pharmacology, Emergency, & Critical Care Proctored Exam – Spring 2025”Exam Code: NURS-450-003

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54M PMHX Of HIN and USA presents with headache, AMS, lethargy. 

ED vitals: 

Temp: 37C 

HR 61 

RR 9 

BP 211/143 

Glucose is 188 

STAT CT head non-con shows the following: 

1st 

4th 

2nd 

3rd 

OR 

remove tournaquit to eval 

ensure a patent airway 

draw labs 

crystalloid bolus 

whole blood via rapid tran 

primary trauma survey 

Matching 1 point 

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Utilizing flashcards focused on areas frequently tested in ATI exams can also enhance your retention and recall of critical information.

50 

FAQs about ATI exams often revolve around test preparation tips, study strategies, and the types of questions encountered. Make sure to engage with resources that can boost your confidence as you tackle your ATI exams.

68M with gunshot wound to the right femoral artery. Obvious exsanguination at scene. Pt arrives to the ED with with a t significantly slowed. AMS and VS as follows: 

HR 122 

BP 65/42 

RR 24 

SpO2 98% on 2L NC 

What’s the priority IN ORDER 

1st 

4th 

2nd 

Multiple Choice 1 point 

A 50-year-old male patient reports having decreased libido and testicular atrophy. The nurse will anticipate that the provi to treat these symptoms? 

Sildenafil (Viagra) 

Finasteride (Proscar) 

Gonadotropin-releasing hormone (Gn-RH) 

Testosterone (Androderm) 

49 

Multiple Choice 1 point 

Myelosuppression 2/2 fluorouracil (5-FU) causes which sequelae? 

leukocytosis, hemoconcentration, thrombocytopenia 

neutropenia, anemia, thrombocytosis 

leukocytosis, anemia, thrombocytopenia 

neutropenia, anemia, thrombocytopenia 

48 

Multiple Choice 1 point 

47 

A 35-year-old woman asks the nurse about oral contraceptives. The nurse learns that the patient smokes and has a fami thromboembolism (VTE). The nurse will suggest that the patient 

will not be a candidate for oral contraceptive products. 

discuss a progestin-only oral contraceptive with her provider. 

may want to consider having a tubal ligation. 

use a transdermal contraceptive product. 

Multiple Choice 1 point 

tendency to bleed during menstruation. 

levels of triglycerides. 

risk for thrombosis. 

incidence of nausea. 

46 

Multiple Choice 1 point 

“In women with established coronary heart disease, EPT can protect against myocardial infarction.” 

“Principle benefits of ET are suppression of menopausal symptoms” 

“EPT is generally safer than ET, especially in women who have undergone hysterectomies.” 

45 

Multiple Choice 1 point 

levothyroxine 

rituximab 

famotidine 

dexamethasone 

44 

Multiple Choice 1 point 

A nurse is providing education to a patient who will begin taking alendronate [Fosamax]. Which complication should the immediately? 

Drowsiness 

Difficulty swallowing 

Dizziness 

Pallor 

43 

Multiple Choice 1 point 

A 45-year-old woman who has not had a period for 15 months reports severe hot flashes and poor sleep. The nurse revi replacement therapy and tells this woman that hormone therapy 

is very safe and may be used freely to treat menopausal symptoms. 

may be used indefinitely to treat menopausal symptoms. 

will be necessary to prevent osteoporosis caused by estrogen depletion. 

should be used at the lowest dose possible for the lease amount of time possible 

42 

Multiple Choice 1 point 

headache 

bone pain 

fatigue 

hemorrhage 

40 

41 

Multiple Choice 1 point 

“I should apply this to my forearms and neck after showering.” 

“I should apply this prior to sexual contact.” 

Multiple Choice 1 point 

nephrotoxicity, HTN, neurotoxicity, dysrhythmia 

hepatotoxicity, HTN, infection, edema 

nephrotoxicity, hypotension, neurotoxicity, dysrhythmia 

hepatotoxicity, tinnitus, neurotoxicity, dysrhythmia 

39 

Multiple Choice 1 point 

The nurse recognizes that which drug is approved for prevention of breast cancer in very high risk individuals? 

Raloxifene 

Tamoxifen 

Toremifene 

Fulvestrant 

38 

Multiple Choice 1 point 

Significant decrease in blood pressure 

Significant increase in pulse rate 

Reduced effectiveness of the sildenafil 

Increased risk of bleeding 

37 

Multiple Choice 1 point 

36 

Which of the following drugs specifically inhibits calcineurin in the activated T lymphocytes? 

Methotrexate 

Mycophenolate mofetil 

Doxorubicin 

Tacrolimus 

Multiple Choice 1 point 

48F with a PMHX of stage 3 breast cancer is admitted for chemotherapy induction. She develops acute SOB and VS are 

Temp 37 C 

HR 144 

RR 32 

BP 87/51 

SpO2 81% 

Common things being common, this is MOST LIKELY: 

Septic Shock 

Pulmonary embolism (PE) 

Aspiration PNA 

Hemorrhagic Shock 

35 

Multiple Answer 1 point 

39F with Crohns disease will be started on infliximab (Remicade). The RN knows the mechanism of action of this drug is 

Select all that apply 

Disrupt the inflammatory process 

Augment the patient’s own immune system 

Neutralize tumor necrosis factor (TNF) 

Delay disease progression 

Reverse symptoms and disease progression 

34 

Multiple Choice 1 point 

How would the nurse best describe the mechanism of action of selective estrogen receptor modulators? 

They can have estrogenic and antiestrogenic activity. 

They are strictly antiestrogenic. 

They are strongly estrogenic. 

They promote hormonal activity of gonadal tissue. 

33 

Multiple Choice 1 point 

increase bone resorption to prevent fractures. 

prevent deep vein thrombosis (DVT). 

decrease her risk of endometrial cancer. 

lower her risk of myocardial infarction (MI). 

32 

Multiple Answer 1 point 

46F is being treated with cyclophosphamide for ovarian cancer. The nurse knows it important to be mindful of which saf cyclophosphamide? 

Select all that apply 

cyclophosphamide must be given through a central line or port if given IV 

tumor lysis syndrome is a potentially fatal side effect 

patient should receive volume before and after infusion to prevent hemorrhagic cystitis 

additional volume should be avoided surrounding cyclophosphamide administration, to avoid the development of 

cyclophosphamide is safe to be given through a peripheral IV 

31 

Multiple Choice 1 point 

28F with a PMHx of polycystic ovarian syndrome (PCOS), obesity, cystic acne, HTN, anxiety, and depression, is admitted 

While the nurse is reconciling her medications, she questions which of the following prescriptions with the provider? 

amlodipine (Norvasc) 

isotretinoin (Amnesteem) 

combination OCP (Yasmin) 

leuprolide (Lupron) 

30 

Multiple Choice 1 point 

A patient with endometriosis is being treated with leuprolide [Lupron Depot]. A nurse is teaching the patient about the d patient indicates understanding of the teaching? 

“I can continue to take the medication if I get pregnant.” 

“I may have menopausal-like symptoms when taking this medication.” 

“I can expect the medication to cure my symptoms.” 

“I will need to take the medication for several years.” 

29 

Multiple Choice 1 point 

59F with a PMHx of ovarian cancer is started on cisplatin (Platinol-AQ). 

The RN is MOST concerned with which lab finding? 

WBC decrease from 6K to 3.9K 

creatinine increase from 0.8 mg/dL to 1.9 mg/dL 

ALT increase from 18 U/L to 33 U/L 

Hgb decrease from 11.8 g/dL to 10.4 g/dL 

28 

Multiple Choice 1 point 

When prescribing Tretinoin (Retin-A) the NP advises the patient to 

advise of seeing the results in one week 

use a sunscreen as the drug is photo sensitizing 

use it with Benzoyl peroxide to minimize irritating effects 

Take a shower every day with medicated soap for better absorption 

27 

Multiple Choice 1 point 

A student RN is rotating through L&D and notices nearly all neonates are receiving phytonadione. He asks his nurse why, intended effect is: 

to decrease neonatal pulse pressure 

to decrease bleeding tendency 

to increase neonatal mental alertness 

to increase red blood cell [RBC] indices 

26 

Multiple Choice 1 point 

57F presents with severe sepsis 2/2 pneumonia. 

PMHx of HTN, ESRD, anemia of chronic disease 

PSHX of liver transplant in 2021, hysterectomy in 2014 

Home medications: 

amlodipine (Norvasc), epoetin alfa (Epogen), ferrous sulfate, mycophenolate mofetil (CellCept) 

The RN know the medication that will most likely be d/c’d 2/2 to the active infection is: 

ferrous sulfate 

mycophenolate mofetil (CellCept) 

amlodipine (Norvasc) 

epoetin alfa (Epogen) 

25 

Multiple Choice 1 point 

A nurse is teaching a patient about the use of tadalafil [Cialis] for erectile dysfunction. Which statement by the patient in teaching? 

“If my erection lasts longer than 4 hours, I should contact my provider.” 

“This drug may cause me to have an erection when I don’t want one.” 

“I should not use ACE inhibitors within 12 hours of using tadalafil.” 

“I should take this drug about 15 minutes before sexual activity.” 

24 

Multiple Choice 1 point 

Which of the following is true about iron therapy is true? 

Anemia should be reassessed after 9 months of therapy. 

Ferrous fumarate contains 20% elemental iron. 

Anaphylactic-like hypersensitivity reactions have occurred from parental replacement. 

Oral preparations should be administered within 2 hours of an antacid. 

23 

Multiple Answer 1 point 

22 

21 

The occupational health nurse is presenting information regarding prevention of skin cancer to a group of workers in an i information should the nurse include in the program? Select all that apply 

Use a sunscreen with at least an SPF of 15 when outside 

Tanning beds do not have the same damaging rays as the sun 

Wear sunglasses that wrap around and block both UVA and UVB rays 

Many antibiotics lose efficacy when the patient is exposed to sunlight 

Do not use expired sunscreen as it may not be as effective 

Multiple Choice 1 point 

The nurse is caring for a patient after the third stage of labor, and the provider orders 20 units of oxytocin to be given int explain to the patient that this drug for which purpose? 

To slow the progression of labor 

To prevent postpartum uterine bleeding 

To allow the cervix to close 

To suppress lactation 

Multiple Choice 1 point 

increased prostate size. 

urinary retention. 

increased hair growth. 

alopecia. 

20 

Multiple Choice 1 point 

A patient is being treated for secondary amenorrhea. The nurse expects which drug to be used to treat this problem? 

Raloxifene (Evista) 

Methylergonovine (Methergine) 

Medroxyprogesterone (Provera) 

Estradiol transdermal (Estraderm) 

19 

Multiple Choice 1 point 

18 

17 

16 

A postpartum patient is receiving methylergonovine to prevent hemorrhage. The nurse assesses the patient and notes a minute, a respiratory rate of 16 breaths per minute, and a blood pressure of 120/80 mm Hg. The patient’s uterus is firm. moderate cramping. Bleeding is minimal. What will the nurse do? 

Request an order to administer the methylergonovine intravenously. 

Continue to monitor and tell the patient to report increased cramping. 

Notify the provider of possible uterine hypertonicity. 

Notify the provider of the patient’s blood pressure. 

Multiple Choice 1 point 

22M presents with 2nd and 3rd degree burns. The burn RN knows that the most likely topical antiinfective to be used to 

bacitracin 

polymyxin B (Neosporin) 

silver sulfadiazine (Silvadene) 

mupirocin (Bactroban) 

Multiple Choice 1 point 

A patient who has been diagnosed with rheumatoid arthritis (RA) for 1 month and has generalized symptoms is taking hig inflammatory drugs (NSAIDs) and an oral glucocorticoid. The provider has ordered methotrexate [Rheumatrex]. The patien methotrexate is necessary. The nurse will tell the patient: 

starting methotrexate early can help delay joint degeneration. 

the patient should take the methotrexate with grapefruit juice. 

a methotrexate regimen can reduce overall costs and side effects of treatment. 

starting methotrexate now will help increase life expectancy. 

Multiple Choice 1 point 

A 68-year-old male patient receives a prescription for 25-mg tablets of sildenafil [Viagra] for erectile dysfunction. When the medication, the nurse will tell him to: 

begin taking one tablet twice daily, 12 hours apart. 

take two tablets 1 hour before sexual activity with a high-fat meal. 

take 25 to 100 mg every 72 hours 

start with one tablet about 1 hour before anticipated sexual activity. 

15 

Multiple Answer 1 point 

Which drugs are approved for treating osteoporosis in men? (Select all that apply.

alendronate [Fosamax] 

raloxifene [Evista] 

teriparatide [Forteo] 

calcitonin 

14 

Multiple Choice 1 point 

A patient has been taking a progestin-only, or “minipill,” OC for 3 months and reports spotting and irregular menstrual cy 

suggest that she use a backup form of contraception until these symptoms resolve. 

question the patient about any possible missed doses of the pill. 

recommend that she take a pregnancy test to rule out pregnancy. 

reassure the patient that this is normal with this form of contraception. 

13 

Multiple Choice 1 point 

A patient has just purchased a 1-year supply of 28-day-cycle oral contraceptives. She tells the nurse she wishes she had she has calculated that her period will begin during her upcoming honeymoon. What will the nurse suggest? 

She should discuss a prescription for an extended-cycle product with her provider. 

She should discuss DMPA (Depo-Provera) injections in addition to the OC with her provider. 

She should discard the inert pills and start a new pack during the honeymoon. 

She should discontinue the oral contraceptives and use an alternative form of birth control. 

12 

Multiple Choice 1 point 

WBC: 0.24 K 

Hgb 7.1 g/dL 

Platelets 26K 

The nurse understands this is a product of the chemotherapy nadir, and expects to give which medications? 

filgrastim, epoeitin alfa 

loperamide, darbepoetin alfa 

oprelvekin, dexamethasone 

sargramostim, tpa 

11 

Multiple Choice 1 point 

29F G2 P1 is 26 weeks + 4 days with spontaneous rupture of membranes and subsequent precipitous delivery. The NI will be given a medication to help prevent respiratory distress syndrome secondary to collapsed alveoli. The medication 

betamethasone IM 

magnesium sulfate IV 

surfactant IH 

methotrexate PO 

10 

Multiple Choice 1 point 

A 42-year-old child who has been receiving high-dose systemic glucocorticoids for several months comes to a clinic for s 

usually include the DTaP vaccine; varicella virus vaccine [Varivax]: the measles, mumps, and rubella virus (MMR) vaccine; vaccine (IPV). The clinic nurse will expect to administer which vaccines to this child? 

DTaP, OPV, and Varivax only 

DTaP and IPV, along with immunoglobulins 

DTaP and IPV only 

All four school immunizations 

Multiple Choice 1 point 

respiratory failure 

fever and tremors 

renal failure 

O agitation 

Multiple Choice 1 point 

The nurse understands that a patient taking tamoxifen (Nolvadex) is at risk for what? 

Hyperlipidemia 

Thromboembolism 

Osteoporosis 

Breast cancer 

Numeric 1 point 

You receive a patient into the ICU from a flight team. Their pump has norepinephrine (Levophed) running at 3.3 mg/hr. mcg/min. How many mcg/min will you program the norepinephrine to run? (just write the number) 

Answer 

Multiple Choice 1 point 

A patient is about to begin therapy with fingolimod [Gilenya] to treat multiple sclerosis. The nurse learns that the patient chickenpox or the varicella zoster virus (VZV) vaccine. What will the nurse do? 

Give the VZV vaccine and tell the patient to begin using fingolimod in 1 month. 

Obtain an order for a VZV antibody test to assess immune status 

Give the VZV vaccine with the initial dose of fingolimod. 

Advise the patient to avoid individuals with chickenpox. 

Multiple Choice 1 point 

38F G1 PO is 33 weeks, and presents to the ED with preeclampsia. The patient is prescribed IV magnesium sulfate. 

The nurse walks into the room to check the patient’s DTRs, and finds her in respiratory distress. 

The RN stays with the patient, calls for help, and has her coworker bring which medication as the antidote? 

sodium phosphate 

potassium chloride 

oxytocin (Pitocin) 

calcium chloride or calcium gluconate 

Ectopy on cardiac monitor 

Echocardiogram with EF of 30% 

HR 108 

BP 82/51 

RR 26 

SpO2 is 86% on HFNC 

Common things being common, this adverse effect 2/2 ILK toxicity is: 

anaphylaxis 

capillary leak syndrome 

cytokine release syndrome 

obstructive shock 

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