Gastrointestinal and Medication Administration Exam – NURS 308 or PNUR 210 | Code: GI-MEDS-SP25

Gastrointestinal and Medication Administration Exam – NURS 308 or PNUR 210 | Code: GI-MEDS-SP25

If you’re taking a proctored nursing exam that covers GI medications, drug calculations, and clinical pharmacology scenarios, you’re not alone — and it’s not easy. From math-based questions like “How many teaspoons of acetaminophen syrup to give?” to case-based questions about GERD meds, antidiarrheals, H2 blockers, and contraindicated drugs like sulfasalazine, the pressure is real — especially under proctoring software like:

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73) A nurse is preparing to administer 650 mg of acetaminophen syrup to a client. The amount available is 

Saved 

acetaminophen syrup 160 mg/5 mL. How many tsp should the nurse administer per dose? (Round the answer to the nearest whole number) 1 Point Extra Credit 

74) A nurse is preparing to administer amlodipine 10 mg PO once per day to a client. The amount available is 

amlodipine 2.5 mg/tablet. How many tablets should the nurse administer? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.

1 Point Extra Credit 

75) A nurse is preparing to administer amlodipine 10 mg PO daily. Available is amlodipine 2.5 mg tablets. How many 

tablets should the nurse administer per dose? (Round the answer to the nearest whole number

1 Point Extra Credit 

Click the button below to submit your test. You will not be able to change your answer after this. 

All answers have been saved

Submit Test 

70) The antidiarrheal agent that acts to stop secretion of fluids that promote diarrhea into the GI tract is: 

1 Point 

0000 

O loperamide (Imodium)

opium (Paregoric). 

bismuth subsalicylate (Pepto-Bismol). 

diphenoxylate (Lomotil). 

71) A nurse is preparing to administer a unitdose medication. Which of the following information should the nurse 

expect to find on the medication label? (Select all that apply.

1 Point Extra Credit 

Administration times 

Generic name 

Storage instructions 

Expiration date 

Client diagnosis 

72) A nurse is administering medications to four clients using an automated dispensing system. Which of the following 

actions should the nurse take to prevent medication administration errors? Select all that apply

1 Point Extra Credit 

Remove the medication from the unit-dose package immediately after removing it from the automated dispensing system. 

Compare the medication label with the medication administration record. 

Document the medication immediately after administering it. 

Check the expiration date on the medication label. 

Take out medications for more than one client at once

73) A nurse is preparing to administer 650 mg of acetaminophen syrup to a client. The amount available is 

acetaminophen syrup 160 mg/5 mL. How many tsp should the nurse administer per dose? (Round the answer to the nearest whole number

1 Point Extra Credit 

65) Patients with cardiac disease should prevent straining and the Valsalva maneuver by

1 Point 

using diuretics. 

reducing fluids. 

stool softeners. 

digital stimulation. 

66) Approximately what portion of the US population experiences heartburn once each month

1 Point 

Saved 

one-half 

three-fourths 

one-third 

one-fourth 

67) Nausea and vomiting in pregnancy can be controlled by dietary measures in most cases. The patient should be 

taught to eat

1 Point 

small, frequent, dry meals. 

fatty foods. 

only 3 meals a day. 

nothing until the nausea subsides. 

68) Approximately how many Americans will develop an ulcer at some time in their lives

1 Point 

5% 

10% 

20% 

15% 

69) A blister most commonly found at the junction of the mucous membrane and the skin of the lips or nostrils is 

called

1 Point 

O a cold sore. 

a canker sore. 

oral mucositis. 

xerostomia. 

Saved 

Saved 

65) Patients with cardiac disease should prevent straining and the Valsalva maneuver by

1 Point 

using diuretics. 

reducing fluids. 

stool softeners. 

digital stimulation. 

66) Approximately what portion of the US population experiences heartburn once each month

1 Point 

one-half 

three-fourths 

one-third one-fourth 

67) Nausea and vomiting in pregnancy can be controlled by dietary measures in most cases. The patient should be 

taught to eat

1 Point 

small, frequent, dry meals. 

fatty foods

only 3 meals a day. 

nothing until the nausea subsides. 

68) Approximately how many Americans will develop an ulcer at some time in their lives? 

1 Point 

5% 

10% 

20% 

15% 

69) A blister most commonly found at the junction of the mucous membrane and the skin of the lips or nostrils is 

called

1 Point 

a cold sore. 

a canker sore. 

oral mucositis. 

xerostomia. 

61) Most health care providers order antacids 

hour(s) before meals

hours after meals, and at bedtime

1 Point 

3:1 to 2 

1;2 to 3 

4;5 to 6 

2; 2 to 4 

62) Canker sores are recurrent aphthous stomatitis and the exact cause is

1 Point 

unknown

virus. 

trauma. 

stress. 

63) An increase in the frequency or fluid content of bowel movements is called

1 Point 

diarrhea. 

flatulence. 

constipation. impaction. 

64) One of the advantages of famotidine is that it is administered 

1 Point 

0000 

weekly

every other week. 

monthly. 

daily. 

65) Patients with cardiac disease should prevent straining and the Valsalva maneuver by

1 Point 

using diuretics. reducing fluids

stool softeners. digital stimulation. 

Sharing desktop with: admin – a 

57) A woman with severe persistent vomiting that interferes with nutrition, fluid, and electrolyte balance may be 

experiencing

1 Point 

0000 

hyperhidrosis. 

primigravida. 

hyperemesis gravidarum. multigravida. 

58) Which type of fungal infection is often called the disease of the diseasedbecause it appears in debilitated 

patients

1 Point 

0000 

fever blister 

canker sore 

cold sore candidiasis 

59) Intestinal infections are most frequently associated with ingestion of food contaminated with

1 Point 

OOOO 

viruses. 

pesticides. 

bacteria. 

fungus. 

60) The most effective treatment for halitosis is

1 Point 

0000 

mouthwash. 

saline rinse

breath mints. brushing teeth. 

53) A nurse is teaching a client who recently had a myocardial infarction and has a new prescription for docusate 

sodium. The nurse should inform the client that docusate sodium has which of the following therapeutic effects? 1.55 Points 

Reduces gastric acid 

Prevents straining 

Prevents diarrhea 

Reduces inflammation 

54) A nurse is caring for a patient who has a new prescription for famotidine to treat GERD. The nurse should instruct 

the client to wait al least 1 hr between famotidine and which of the following overthecounter drugs? 1.55 Points 

St. John’s wort 

Antacids 

Antidiarrheals 

Ginkgo biloba 

55) A nurse is planning teaching to a client who has been prescribed loperamide to treat diarrhea. Which of the 

following statements should the nurse plan to include

1.55 Points 

“If you miss a dose, double the next dose.” 

“Rinsing the mouth with alcohol-based mouthwash can reduce dryness.” 

“Avoid driving or activities requiring alertness.” 

“Having one glass of wine each night can improve medication effectiveness.” 

56) Which type of inactive enzyme do chief cells secrete

1 Point 

0000 

pepsinogen 

hydrochloric acid 

intrinsic factor 

mucus 

49) Which of the following is the most frequent side effect produced by antidiarrheal drugs? 

1.55 Points 

Renal failure 

Constipation 

Vomiting Hypertension 

50) What is the action of saline laxatives

1.55 Points 

Promoting peristalsis by drawing water from blood plasma to increase the volume of the intestinal contents Absorbing water into the stool mass and then expanding, promoting peristalsis 

Stimulating peristalsis through contact with the intestinal mucosa 

Softening the fecal mass, allowing for easier passage of contents 

51) A nurse is reviewing the medical record of a client who has a new prescription for famotidine. The nurse should 

recognize that which of the following drug interacts with famotidine

1.55 Points 

0000 

Ketoconazole 

Lisinopril 

Hydrochlorothiazide Phenobarbital sodium 

52) A female client of childbearing age is starting therapy with misoprostol taking omeprazole to prevent a gastric 

ulcer. Which of the following instructions should you include when talking with the client about this drug? Select all that apply

1.55 Points 

10000 

Report excessive menstrual pain. 

Mid-cycle spotting can occur. 

Avoid taking the drug a bedtime. 

Use effective contraception. 

Take pregnancy test prior to therapy. 

45) A client is about to start taking alosetron to treat diarrhea. You should instruct the client to watch for and report 

which of the following adverse reactions of this drug

1.55 Points 

1000 

Confusion 

Difficulty swallowing 

Constipation 

Blurred vision 

46) A patient reports severe abdominal pain that occurs approximately 45 to 60 minutes after eating. The patient 

notes that eating dairy products or drinking milk alleviates the pain but eating Mexican food or drinking alcohol worsens the condition. The health care provider orders xrays to be done in several days, but in the meantime, which type of drug will likely be recommended

1.55 Points 

0000 

Antacid 

Laxative 

Antiflatulent Anticholinergic 

47) Which of the following drugs has protocols that require clients to meet specific risk-management criteria and sign 

a treatment agreement before the nurse can administer the drug

1.55 Points 

Azathioprine 

Alosetron 

Lubiprostone 

Sulfasalazine 

48) A patient who is suffering from postoperative nausea vomited 20 minutes after arriving in the recovery room and 

now is retching. Additionally, the patient is dizzy and lightheaded and has a very slow pulse. What is the patient experiencing

1.55 Points 

0000 

Anticipatory nausea and vomiting 

Motion sickness 

Autonomic nervous system response 

Vasovagal response 

41) A nurse is providing teaching to a client who is about to start taking psyllium to treat constipation. Which of the 

following instructions should the nurse include? Select all that apply

1.55 Points 

Expect results in 6 to 12 hr. 

00000 

Urinate every 4 hr. 

Take the drug with at least 8 oz (237 mL) of fluid. 

Avoid activities that require alertness. 

Increase fluid and fiber intake. 

42) Which oral disorder is contagious

1.55 Points 

Mucositis 

Xerostomia 

Fever blisters 

Canker sores 

43) A nurse should recognize that diphenoxylate/atropine should be used with caution for a client who has which of 

the following conditions

1.55 Points 

0000 

Inflammatory bowel disease 

Agranulocytosis 

Thrombophlebitis 

Immunization with a live virus vaccine within the last 6 weeks 

44) A nurse should recognize that sulfasalazine is contraindicated for clients who have which of the following 

conditions

1.55 Points 

Aspirin sensitivity 

Pancreatitis 

Bronchitis 

GERD 

36) A nurse is teaching a client who has a new prescription for sulfasalazine. Which of the following statements should 

the nurse make

1.55 Points 

“Use sunscreen and protective clothing while taking sulfasalazine to prevent sunburn.” 

“The medication can color your urine dark brown.” 

“Take an iron supplement when you take sulfasalazine to prevent anemia.” 

“The medication can stain your contact lenses green.” 

37) In the context of the treatment of peptic ulcer caused by H. pylori, triple therapy refers to using 

1.55 Points 

two antibiotics and a bismuth compound 

an antibiotic, a bismuth compound, and a proton pump inhibitor 

two antibiotics and a proton pump inhibitor 

an antibiotic, an antifungal, and a bismuth compound 

38) What is the therapeutic role of bismuth in triple therapy that is used to treat peptic ulcers? 

1.55 Points 

Bismuth eradicates the bacterial infection by selectively killing H. pylori. 

Bismuth inhibits the adhesion of bacteria to the gastric mucosa. 

Bismuth permeates the bacterial cell wall and weakens it. Bismuth neutralizes the acid present in the stomach. 

39) Toxic doses of diphenoxylate could produce respiratory depression and coma similar to overdose. 

1.55 Points 

barbiturate 

opiate 

ephedrine 

psychogenic 

40) Oral H2-receptor antagonists 

1.55 Points 

must be taken on an empty stomach 

interact with citrus juices 

O can be taken with food 

do not interact with other medications 

32) The nurse practitioner is caring for a patient who is experiencing xerostomia. Which type of treatment does the 

nurse prescribe for the patient

1.55 Points 

Surgical removal 

Antibiotics 

Saliva substitute 

Antiviral ointment 

33) The nurse administers an antidiarrheal medication to a patient who is experiencing significant diarrhea. Which 

other measure may be taken to improve the patient’s condition

1.55 Points 

Increase fiber in the patient’s diet. Increase the patient’s fluid intake. Increase the patient’s level of activity. Encourage the use of a laxative. 

34) A nurse is caring for a client who is taking allopurinol to treat gout and has anew prescription to treat ulcerative 

colitis. For which of the following reasons should the nurse clarify these prescriptions with the provider? 1.55 Points 

0000 

Azathioprine decreases the effectiveness of allopurinol. 

Azathioprine increases the effectiveness of allopurinol. 

Allopurinol delays the conversion of azathioprine and can lead to toxicity. 

Allopurinol increases the metabolism of azathioprine and can require an increased dosage. 

35) What percentage of the North American population experiences chronic constipation

1.55 Points 

10

15

20% 

25% 

28) Ray is prescribed sucralfate for the treatment of peptic ulcers. Which of the following side effects can Ray expect 

from this medication? 

1.55 Points 

0000 

Vomiting 

Headache 

Constipation 

Nausea 

29) A client is about to start taking omeprazole to treat duodenal ulcer. Which of the following instructions should you 

include when talking with the client about this drug

1.55 Points 

0000 

Avoid using aluminumbased antacids. Consume adequate amounts of fluids. 

Take it with food

Do not drink grapefruit juice. 

30) The suppression of acid secretion is greater with a proton pump inhibitor than with an H2-receptor antagonist 

because

1.55 Points 

0000 

unlike an H2-receptor antagonist, a proton pump inhibitor stimulates H1-receptors. unlike an H2-receptor antagonist, a proton pump inhibitor blocks the secretion of HCI. 

unlike an H2-receptor antagonist, a proton pump inhibitor increases the volume and strength of acid secretion. O unlike an H2-receptor antagonist, a proton pump inhibitor blocks the release of histamine from parietal cells. 

31) A nurse is assessing a client who was administered ondansetron (Zofran) IV 1 hr ago. Which of the following 

findings should the nurse recognize as an adverse effect of this drug

1.55 Points 

0000 

Dyspepsia 

O Bradycardia 

Tardive dyskinesia 

Dizziness 

24) Which H2-receptor antagonist should not be prescribed for a patient already taking calcium channel blockers, 

metoprolol, and phenytoin

1.55 Points 

0000 

Famotidine 

Ranitidine 

Cimetidine 

Nizatidine 

25) 

are considered to be ulcerogenic because they inhibit the secretion of protective mucus and interfere with the normal production of the mucosal lining. 

1.55 Points 

Adrenergic drugs 

Steroids 

Antacids 

Antihistamines 

26) A nurse is planning care for a client who is receiving chemotherapy and has anew prescription for ondansetron

Which of the following actions should the nurse plan to take? Select all that apply

1.55 Points 

Infuse the drug 30 min prior to chemotherapy. 

Administer the drug immediately following chemotherapy. 

Administer the drug when the patient reports nausea. 

Repeat the dose 4 hr after chemotherapy. 

Infuse the drug slowly over 15 min. 

27) Julian is diagnosed with Zollinger-Ellison syndrome and presents with symptoms such as gastric acid hypersecretion. 

Which of the following drugs should be used to treat Julian? 

1.55 Points 

0000 

Omeprazole 

Metoclopramide 

Cimetidine 

Antacids 

20) To prevent future oral problems in children, when should regular oral care begin

1.55 Points 

0000 

When the child enters kindergarten 

At infancy, by rubbing the gums with gauze to cleanse When the child is old enough to hold a toothbrush When teeth first erupt 

21) A nurse is providing teaching to a client who has a new prescription for dimenhydrinate to prevent motion 

sickness. Which of the following instructions should the nurse include? Select all that apply

1.55 Points 

Avoid activities that require alertness. 

Take the drug 30 to 60 min before activities that trigger nausea. 

Increase fluid and fiber intake. 

Sit upright for 30 min after taking the drug. 

Avoid antacids when taking the drug. 

22) The mechanism of action of sucralfate has it classified as 

1.55 Points 

000 

an antacid 

a prostaglandin 

an anticholinergic 

none of the above 

23) Which population is more prone to longlasting effects of anesthetic drugs

1.55 Points 

Elderly 

Obese 

Infants 

Toddlers 

16) Which antiemetic is especially helpful in treating nausea and vomiting resulting from chemotherapy

1.55 Points 

0000 

Prochlorperazine (Compazine) 

Ondansetron (Zofran) Trimethobenzamide (Tigan) Chlorpromazine (Thorazine) 

17) Krista is suffering from GERD. After various medications fail to improve her condition, Krista is prescribed 

metoclopramide as a short-term treatment option. However, the success of the treatment prompts Krista to continue using the medication for over three times the prescribed duration. Krista is at a risk for 1.55 Points 

0000 

bulimia 

O diabetic gastroparesis 

tardive dyskinesia 

sinus tachycardia 

18) A client is about to start taking sulfasalazine to treat inflammatory bowel disease. You should instruct the client to 

watch for and report which of the following adverse effects of this drug? Select all that apply

1.55 Points 

00000 

Joint pain 

Constipation 

Sore throat 

Fever 

Dry mouth 

19) The nurse is providing teaching to a client who has a new prescription for loperamide. Which of the following 

instructions should the nurse include

1.55 Points 

0000 

Dissolve the powder thoroughly in 8 oz of water. Avoid activities that require alertness. 

Take 30 min before activities that trigger nausea. 

Have diphenhydramine available. 

12) Liam consults a doctor as he has been suffering from diarrhea for two days. The doctor prescribes diphenoxylate to decrease peristalsis. Which of the following statements, if true, would indicate that the doctor’s prescription is inappropriate for Liam

1.55 Points 

000 

Liam complains of constipation after taking the drug. 

Liam’s electrolyte levels have changed. Liam shows symptoms of liver disease. 

Liam suffers from lactose intolerance. 

13) A client is about to start taking aluminum hydroxide to reduce gastric acid. Which of the following instructions 

should you include when talking with the client about this drug? Select all that apply

1.55 Points 

1000 

Drink a glass of water after taking it. 

Take it once daily. 

Chew the tablets thoroughly. 

Increase fluid and fiber intake. 

Take the drug with a large meal. 

14) In which patient would you not use a laxative

1.55 Points 

A patient with a colonoscopy ordered tomorrow 

A patient with constipation 

A patient with sudden abdominal pain of unknown cause 

A patient on bedrest, unable to move his or her bowels for 5 days 

15) Identify the mechanism of action by which NSAIDs cause peptic ulcers. 

1.55 Points 

Blockade of prostaglandins that inhibit gastric secretions 

Blockade of receptors that promote the fight-or-flight response 

Stimulation of H1-receptors on smooth muscles of the gastrointestinal tract 

Stimulation of histamine receptors on parietal cells 

8) A nurse is caring for a client who has peptic ulcer disease. The nurse should monitor the client’s phosphorus levels 

when administering which of the following drugs

1.55 Points 

Famotidine 

Sucralfate 

Aluminum hydroxide 

Omeprazole 

9) Select the reason why increased dietary fiber is a major component in the management of constipation. 

1.55 Points 

Fiber increases stool bulk and fluid content and decreases transit time, resulting in an increase in the frequency of defecation. 

Fiber affects the fluid and electrolyte supplements in the stomach and inhibits the sympathetic nervous system, resulting in an increase in the frequency of defecation. 

Fiber decreases the number of microorganisms in the gastrointestinal (GI) tract, decreases the fluid content, and decreases transit time, resulting in a decrease in the frequency of defecation. 

None of these are correct. 

10) How long does the breathfreshening action of overthecounter mouthwashes last? 

1.55 Points 

10 to 30 minutes 

1 to 2 hours 

3 hours 

30 to 60 minutes 

11) The nurse is teaching a patient about metoclopramide (Reglan) therapy. Which patient statement indicates to the 

nurse that the patient has a correct understanding of the therapy

1.55 Points 

00 

“This drug will slow down the acid being produced in my stomach.” This medication will make my digestive system move faster.” “I’ll be able to return to my job as a truck driver tomorrow.” “By coating my stomach, this medication will reduce my stomach upset.” 

4) Omeprazole works by 

1.55 Points 

Inhibiting a hydrogen-potassium pump in mucosal cells nhibiting a sodium-potassium pump in parietal cells inhibiting a hydrogen-potassium pump in parietal cells inhibiting a sodium-potassium pump in mucosal cells 

5) Famotidine is available as over-the-counter 10-mg tablets. If Kayla takes one tablet every 12 hours over a period of 

four days. What is the total dosage of famotidine administered to Kayla? 

1.55 Points 

40 mg 

120 mg 

80 mg 48 mg 

6) A nurse is caring for an older adult client who has kidney disease and a new prescription for cimetidine. The nurse 

should instruct the client to report which of the following manifestations

1.55 Points 

000 

Lethargy 

O Myalgia 

Dry mouth Cellulitis 

7)_____results when antacids increase the pH of the stomach and the secretory cells respond by increasing the 

secretion of gastric acid. 

1.55 Points 

0000 

Hypercalcemia 

Acid rebound 

Hypophosphatemia 

Acid reflux 

Saved 

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